Q2｜Why We Insist on “Freeze-Dried Powder + Diluent”

In 2013, the Nobel Prize in Physiology or Medicine established the cellular “vesicle trafficking” mechanism—essentially the instruction manual for how cells package and deliver signals. That insight helps us understand and modulate exosome formation and release, opening possibilities in skin and aesthetic care. Exosomes have since been widely explored as one of the most promising ways to break long-standing bottlenecks in regeneration and repair.

 

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TL;DR (One-Sentence Takeaway)

Freeze-drying = freshness & stability. Fresh reconstitution = peak activity + a hygienic, one-use loop.

Exosomal cargo is highly sensitive to temperature, oxidation, and microbes. Keeping it freeze-dried “pauses the clock.” Reconstituting right before use aligns peak performance with the 0–60 min post-microneedling window, optimizing efficacy, feel, and hygiene in one move.

 

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01｜What does freeze-drying actually lock?

• Structural integrity: low-temp vacuum dehydration helps preserve the lipid bilayer and the payload (proteins/peptides/lipids/nucleic-acid fragments).
  
  

• Activity retention: minimizes oxidation, shear, and thermal drift that can slowly degrade actives in water.
  
  

• Cleaner formulas: better room-temperature tolerance reduces reliance on heavy preservative systems; the result feels lighter and gentler for reactive skin.
  
  

Plainly put: we bottle the “lab-fresh state” so you can open it at the right moment.

 

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02｜Why reconstitute right before use? Hit 

peak activity

 in the 

golden window

Microneedling creates controlled microchannels in the epidermis. The 0–60 minute period afterwards is critical for delivery and comfort.

• On-demand workflow: reconstitute in ~10 seconds → dot/apply or guided infusion → calming mask for 10–15 minutes.
  
  

• Feel it fast: tightness, dryness, and visible redness often calm more quickly; over 2–4 weeks, texture and clarity are easier to see and feel with consistent cadence.
  
  

 

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03｜Why not just a ready-made water serum?

 

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04｜Why only the dedicated diluent?

Our diluent is not “just water.” It’s a skin-friendly medium engineered for exosomes:

• Isotonic + skin-friendly pH to reduce sting and osmotic discomfort;
  
  

• Gentle buffering to keep pH steadier for 24–48 hours after reconstitution;
  
  

• High purity / low endotoxin to cut unknown variables.
  
  

Bottom line: don’t substitute with purified water or DIY saline. Use the provided diluent only.

 

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05｜Why we 

never ship pre-reconstituted

 product

• Fragile after mixing: once in solution, sensitivity to heat and agitation rises sharply.
  
  

• Higher contamination risk: extended logistics windows increase hygiene risk.
  
  

• Missed peak: if peak activity occurs before you actually use it, potential is wasted.
  
  

So we hand the “reconstitution moment” back to you (or your clinic) to keep the best moment at the point of use.

 

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06｜Our delivery promise: 

Fresh-Batch 48h

We turn “freshness & traceability” into a visible service:

• Ship within 48 hours of your order;
  
  

• Allocate the latest released batch, print per-vial labels (LOT, Vial-ID, release/production date, spec, storage);
  
  

• QR code to your Trace Page: batch COA summary, outbound temperature-control notes, and usage tips;
  
  

• Heat-season thermal packaging as needed. If a temp excursion or seal breach occurs, we follow an SOP for priority replacement.
  
  

 

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07｜How to reconstitute & use (quick SOP)

Clinic day (D0)

1. Cleanse/disinfect → microneedling 0.25–0.5 mm by zones.
   
   

2. Add diluent along the vial wall, gently invert to mix (avoid vigorous shaking).
   
   

3. Apply the full vial to the target area.
   
   

4. Calm with a 10–15-minute cooling mask.
   
   

5. Rest of day: moisturize + broad-spectrum/physical sunscreen only.
   
   

At-home stabilization (non-invasive)

• We don’t recommend DIY microneedling. Post-cleanse, dot/soak 1–2×/week.
  
  

• If you must split a vial: refrigerate 2–8 °C and finish within 48 hours. Stop use if you notice discoloration, off-odor, or flocculent precipitate.
  
  

 

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08｜Dosing & cadence

• 1 freeze-dried vial + 1 diluent vial = 1 standard session.
  
  

• Suggested rhythm: every 7–10 days; 3 sessions ≈ one condensed cycle.
  
  

Sets

• Pro (1+1): single session / entry.
  
  

• Max (2+2): intensive two-week stabilization.
  
  

• Ultra (3+3): 3–4 week condensed cycle—worry-free before key events.
  
  

 

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09｜Quick Q&A

Q: Can I split a vial into two uses?

A: Best practice is one vial = one use. If you must split: seal, refrigerate 2–8 °C, use within 48h.

Q: A slight opalescence or tiny bubbles after reconstitution—is that normal?

A: Often yes (light scattering / microbubbles). Stop use if you see obvious discoloration, persistent precipitate, or off-odor.

Q: Can I pair with an infusion device or LED?

A: Yes—gentle, low-heat physical modalities are preferred. Energy/heat devices must follow your clinic SOP (timing & intensity).

Q: Why emphasize the label and QR code so much?

A: Per-vial traceability is our trust baseline: LOT/Vial-ID, release info, and temperature data—one bottle, one clear history.

 

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10｜PDP Highlights (consumer-friendly)

• Dual-chamber freshness, used right away: peak activity right in the post-microneedling golden window.
  
  

• One vial = one use: standardized dosing, hygienic loop, peace of mind.
  
  

• Fresh-Batch 48h: latest released batch + per-vial traceability + temperature-aware fulfillment.
  
  

 

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Compliance & scope note (site-wide reusable)

Our products are cosmetics intended for surface-level skincare—hydration, soothing, and supporting the skin barrier. They are not intended to diagnose, treat, cure, or prevent any disease. Any research/case materials shared on-site are for educational context only and do not constitute individual performance guarantees or medical advice. Always follow professional guidance for in-clinic procedures and aftercare.