From Order to Dispatch, How We Ensure You Receive the Newest Release Lot

Background. In 2013, the Nobel Prize in Physiology or Medicine clarified the core mechanics of cellular vesicle trafficking—essentially a handbook for understanding and steering exosome formation and release. That breakthrough opened broad possibilities in skin and aesthetic care, and exosomes are now viewed as one of the 21st century’s most promising ways to overcome bottlenecks in regeneration and repair.

Why “Fresh-Batch 48h” matters

Exosomes are finely tuned biological signal carriers. The lyophilized (freeze-dried) + fresh reconstitution format best preserves structure and function. Batch freshness and end-to-end traceability determine whether each vial in your hand performs like it did in the lab.

Our promise: within 48 hours of your order, we dispatch the newest release lot and provide per-vial traceability.

The 48-hour timeline (starts the moment you click “Order”)

 

T+0 h｜Order received

Order enters LIMS (Laboratory Information Management System). We lock the matching lot size (e.g., 10 Billion/vial). You receive a “Fresh-Batch candidate” notice.

 

T+6–18 h｜Release lot matching

Production & QC align on lots ready to release this day/week.

Key checks: particle size/distribution (e.g., NTA), exosome markers (CD9/CD63/CD81), endotoxin/bioburden, pH/osmolality, appearance.

The newest lot with adequate inventory is assigned; if none qualifies, the system rolls to the next release window.

T+18–36 h｜Per-vial labels

Each lyophilized vial and solvent receives a unique ID:

LOT (batch) + Vial-ID + date/shift + spec/dose.

QR code links directly to that vial’s Trace Page (COA summary, storage/use notes, outbound temperature record).

Dual human review + e-signature.

T+36–44 h｜Temperature-ready packing & pre-dispatch QC

Lyophilized vial: packed dry and light-protected at ambient.

Solvent: insulated shipper + cold packs + temperature logger.

Tamper-evident seals and “handle with care/dry keep” labels.

We scan a pre-dispatch snapshot (box temp, pack time, packer).

T+44–48 h｜Handover to carrier

We push tracking and a temperature-trace link.

If extreme weather/holidays/cross-border timing risks freshness, the system applies a “delay strategy” (ships on the next release day to preserve temp control and freshness).

In one line: newest release lot + per-vial trace + outbound temp control—completed within 48 hours.

Why we never ship 

pre-mixed

(reconstituted) product

 

1. Stability. Lyophilized exosomes tolerate transport far better. Once reconstituted, protein/lipid structures become sensitive to heat swings and shear.

2. Sterility & risk. Even with cold chain, transit can add contamination opportunities. Keeping reconstitution at your side (or in-clinic) maximizes freshness and cleanliness.

3. Peak activity. Mix right before use so the peak window aligns with your care protocol and timing (e.g., post-needling window).

What you can verify (per-vial traceability)

 

On-label: LOT, Vial-ID, date, spec (e.g., 10B), EXP, storage condition, QR.

Trace Page (via QR):

• COA summary: particle size/markers, microbial limits, heavy metals, pH/osmolality.

• Temperature curve for the solvent leg; pack and handover timestamps; out-of-range flags and fast-replacement path.

• “How-to”: reconstitution volume/steps, post-procedure 0–60 min window, 48 h finish rule.

  Order progress: four milestones—T+0 / T+18 / T+36 / T+48—clearly shown.

 

What the packaging looks like

• Outer carton: multilayer board + moisture barrier + shock-absorbing foam.

• Insulated liner: EPP/vacuum panels + cold packs (solvent leg). Validated 72 h profiles for ambient and summer lines.

• Temperature logger: auto-generates a PDF at delivery (useful for clinics).

• Tamper control: if the seal is compromised, we replace according to our after-sales SOP.

After delivery: how to store & how to mix

Storage

• Lyophilized vial: keep dry; 2–8 °C preferred; avoid humidity and repeated openings.

• Solvent: 2–8 °C; once opened, use promptly.

Reconstitution

• Use only the provided sterile solvent; run it down the inner wall; gently invert to mix (no vigorous shaking).

• Best practice: reconstitute and use immediately. If you must split, keep sealed, protected from light, refrigerate 2–8 °C, and finish within 24–48 h.

Pairing

• Procedure day: cleanse/disinfect, then use within 0–60 min post-needling.

• Days 1–3: thin application as needed; avoid friction and stacked irritants.

Quick Q&A

Q1: Why must you dispatch within 48 h?

Because that is the optimum balance for “newest release lot + per-vial trace + temperature-ready packing” while minimizing your wait.

Q2: Can I pick the exact batch number?

The system assigns the newest lot with healthy stock. If you have a research/regulatory need, add a note at checkout and we’ll try to accommodate.

Q3: Can you send it already reconstituted?

No. Reconstituted material demands strict temperature/asepsis; transit uncertainty would impair activity and safety margins.

Q4: How do I know it didn’t overheat in transit?

Each parcel includes a temperature logger. Scan to view the curve. If out-of-range is flagged, we replace per SOP.

Q5: Will cross-border shipments be slower?

They can be; routes and customs vary. We balance ship date and temp plan by destination/weather—better to wait for the next release day than compromise freshness.

One-line wrap

Fresh-Batch 48h is not about speed; it’s about disciplined freshness, activity, and traceability. When you receive the two bottles—a lyophilized vial and a solvent—you receive the newest release lot, per-vial evidence, and a delivery you can verify.

 

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4 blog images for this article

1) Fresh-Batch 48h Timeline (hero graphic)

Alt text: “Horizontal timeline showing T+0, T+6–18, T+18–36, T+36–44, T+44–48 with key steps: LIMS, release matching, labeling & QR, temperature-ready packing, dispatch.”

2) Why We Never Ship Reconstituted (three-panel explainer)

Alt text: “Three panels labeled Stability, Sterility, Peak Activity explaining why only fresh reconstitution is used.”

3) Per-Vial Traceability Modules

Alt text: “Mock label on the left (LOT/Vial-ID/QR) and Trace Page modules on the right (COA summary, temperature curve, how-to).”

4) Packaging & Post-Delivery Guide

Alt text: “Cutaway of shipping box (outer carton, insulation, cold packs) plus a checklist of what to do after delivery.”

Suggested placement

• Image 1 under the H1 as the hero.

• Image 2 beneath the “Why we never ship pre-mixed” section.

• Image 3 under “What you can verify.”

• Image 4 under “What the packaging looks like / After delivery.”

Compliance note: Our products are cosmetics. Claims relate to cleansing, hydration, comfort/soothing and barrier support. They are not intended to diagnose, treat, cure or prevent any disease.